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Lars Knudsen Selected Research

Surfactant Dysfunction

1/2020Hidden Microatelectases Increase Vulnerability to Ventilation-Induced Lung Injury.
1/2017Surfactant replacement therapy reduces acute lung injury and collapse induration-related lung remodeling in the bleomycin model.
7/2015Linking progression of fibrotic lung remodeling and ultrastructural alterations of alveolar epithelial type II cells in the amiodarone mouse model.
5/2014Effects of exogenous surfactant on the non-heart-beating donor lung graft in experimental lung transplantation - a stereological study.

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Lars Knudsen Research Topics

Disease

12Fibrosis (Cirrhosis)
01/2022 - 01/2013
11Pulmonary Fibrosis (Fibrosing Alveolitis)
01/2021 - 09/2012
10Lung Injury
02/2021 - 01/2013
8Lung Diseases (Lung Disease)
01/2020 - 10/2005
7Edema (Dropsy)
01/2020 - 04/2005
6Idiopathic Pulmonary Fibrosis
01/2022 - 02/2015
6Emphysema
05/2017 - 12/2004
5Inflammation (Inflammations)
01/2021 - 08/2010
5Reperfusion Injury
05/2014 - 04/2005
4Surfactant Dysfunction
01/2020 - 05/2014
4Hyperplasia
01/2017 - 12/2004
3ST Elevation Myocardial Infarction
01/2022 - 10/2012
3Hypertrophy
01/2017 - 12/2004
3Primary Graft Dysfunction
05/2014 - 06/2011
3Ischemia
01/2012 - 03/2010
2Interstitial Lung Diseases (Interstitial Lung Disease)
01/2021 - 03/2017
2Acute Lung Injury
01/2020 - 01/2017
2Pulmonary Emphysema
12/2013 - 02/2009
1Disease Progression
09/2021
1Newborn Respiratory Distress Syndrome
01/2021
1Pulmonary Alveolar Proteinosis
01/2020
1Ventilator-Induced Lung Injury
01/2020
1Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
01/2020
1Body Weight (Weight, Body)
12/2018
1Weight Loss (Weight Reduction)
03/2017
1Shock
04/2015
1Out-of-Hospital Cardiac Arrest
04/2015
1Necrosis
06/2014
1Heart Arrest (Cardiac Arrest)
05/2014
1Heart Failure
05/2014
1Asthma (Bronchial Asthma)
04/2014
1Respiratory Hypersensitivity
04/2014
1Pneumonia (Pneumonitis)
04/2014
1Metaplasia
04/2014
1Lipoid Proteinosis of Urbach and Wiethe (Lipoidproteinosis)
12/2013
1Pneumothorax
02/2013
1Wounds and Injuries (Trauma)
01/2013
1Critical Illness (Critically Ill)
10/2012
1Familial Primary Pulmonary Hypertension
12/2011
1Infections
08/2010

Drug/Important Bio-Agent (IBA)

19Surface-Active Agents (Surfactants)IBA
01/2021 - 12/2004
12Bleomycin (Blenoxane)FDA LinkGeneric
01/2022 - 09/2012
9Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA
05/2017 - 12/2004
6CollagenIBA
01/2021 - 02/2009
6Proteins (Proteins, Gene)FDA Link
01/2021 - 08/2010
3indium-bleomycinIBA
01/2021 - 01/2013
3Amiodarone (Amiodarona)FDA LinkGeneric
10/2015 - 11/2014
3Iloprost (Ventavis)FDA Link
12/2011 - 04/2005
2Valine (L-Valine)FDA Link
01/2021 - 03/2017
2Azithromycin (Zithromax)FDA LinkGeneric
01/2020 - 01/2020
2Pharmaceutical PreparationsIBA
01/2020 - 01/2020
2poractant alfa (Curosurf)FDA Link
01/2017 - 01/2012
2Hydroxyproline (4 Hydroxyproline)IBA
11/2014 - 01/2013
2Protein CIBA
01/2013 - 01/2012
2Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
01/2013 - 01/2013
2ProstaglandinsIBA
10/2005 - 04/2005
2Epoprostenol (Prostacyclin)FDA LinkGeneric
10/2005 - 04/2005
1Keratins (Keratin)IBA
01/2022
1Codon (Codons)IBA
01/2021
1Glutamic Acid (Glutamate)FDA Link
01/2021
1Granulocyte-Macrophage Colony-Stimulating Factor Receptors (GM-CSF Receptor)IBA
01/2020
1pirfenidoneIBA
01/2020
1Ligases (Synthetase)IBA
01/2020
1UbiquitinIBA
01/2020
1ProteomeIBA
01/2020
1Autophagy-Related ProteinsIBA
11/2019
1Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
11/2019
1Cathepsin AIBA
11/2019
1Tyrosine (L-Tyrosine)FDA Link
10/2019
1LigandsIBA
10/2019
1Interleukin-6 (Interleukin 6)IBA
01/2019
1Interleukin-18 (Interleukin 18)IBA
01/2019
1Interleukin-10 (Interleukin 10)IBA
01/2019
1Lysine (L-Lysine)FDA Link
03/2017
13-hydroxy-5-estrane-17-carbonitrile (ACN)IBA
02/2017
1Saline SolutionIBA
01/2017
1Cathepsin DIBA
11/2014
1CalciumIBA
06/2014
1MicroRNAs (MicroRNA)IBA
04/2014
1Interleukin-5 (Interleukin 5)IBA
04/2014
1OvalbuminIBA
04/2014
1Nitric Oxide Synthase (NO Synthase)IBA
01/2014
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2013
1beractant (Survanta)FDA Link
01/2012
1Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
12/2011
1Endothelin Receptor AntagonistsIBA
12/2011
1Collectins (Collectin)IBA
08/2010

Therapy/Procedure

7Therapeutics
09/2021 - 12/2011
5Lung Transplantation
05/2014 - 04/2005
4Artificial Respiration (Mechanical Ventilation)
02/2021 - 12/2018
3Transplantation
01/2021 - 05/2014
2Percutaneous Coronary Intervention
01/2022 - 10/2012
1Cell Transplantation
01/2021
1Immunotherapy
10/2019
1Lasers (Laser)
12/2015
1Cardiopulmonary Resuscitation (CPR)
04/2015
1Surgical Amputation (Amputations)
06/2014
1Time-to-Treatment
07/2013
1Positive-Pressure Respiration (Positive End-Expiratory Pressure)
02/2013
1Transportation of Patients
10/2012